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More rapid administration may result in respiratory depression and enhanced pressor response.

General: -Because of rapid induction following the initial IV injection, the patient should be in a supported position during administration.

Applies to the following strength(s): 100 mg/m L ; 50 mg/m L ; 10 mg/m L ; 10 mg/m L-Na Cl 0.9% ; 1 mg/m L-Na Cl 0.9% ; 50 mg/5 m L ; 100 mg/10 m L ; 50 mg/5 m L-Na Cl 0.9% ; 100 mg/10 m L-Na Cl 0.9% The information at is not a substitute for medical advice. IV: -Induction: 1 to 4.5 mg/kg IV; alternatively, 1 to 2 mg/kg IV at a rate of 0.5 mg/kg/min; (2 mg/kg dose provides 5 to 10 minutes of surgical anesthesia within 30 seconds) -Maintenance: The maintenance dose should be adjusted according to the patient's anesthetic needs and whether an additional anesthetic is employed.

Increments of one-half to the full induction dose may be repeated as needed for maintenance of anesthesia.

-Elevation of blood pressure begins shortly after injection, reaches a maximum within a few minutes and usually returns to preanesthetic values within 15 minutes after injection.

16 years and older: See adult dosing Data not available Data not available -The individual response is somewhat varied depending on the dose, route of administration, and age of patient, so that the dosage recommendation cannot be absolutely fixed.

The drug should be titrated against the patient's requirements.

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